Frederica Sawyer (フレデリカ・ソーヤー, Furederika Sōyā),[1][2] also known as Sawyer the Cleaner (掃除屋ソーヤー Sōjiya Sōyā) or simply Sawyer (ソーヤー Sōyā), is a young girl who specializes in corpse disposal in Roanapur. In addition to her regular job, Sawyer is also a freelancer who partners up with her friends Shenhua and Lotton. She is also the titular character of the first official Black Lagoon spinoff series Dismemberment Galore! The Gore Gore Girl.

Chang Wai-San (張 維新チャン・ウァイサン Chan Waisan),[1] also known as Mister Chang (張の旦那 Chan no danna; ミスター張 Misutā Chan) or his lesser-used Triad title Bai Ji-Shin (Chinese: 白紙扇 Báizhǐ shàn, lit. "White Paper Fan"),[2] is the boss of the Thai branch of the Hong Kong Triad in Roanapur.

Maid living in Venezuela working for the Lovelace family

Balalaika is a prominent character in the anime and manga series "Black Lagoon." She is the leader of Hotel Moscow, a powerful Russian mafia organization operating in the fictional city of Roanapur. Balalaika is a tall, imposing woman with a stoic demeanor and a distinctive facial scar. She is a skilled marksman and tactician, known for her ruthless and strategic approach to achieving her goals. Despite her hardened exterior, Balalaika possesses a complex and multi-dimensional personality, showcasing both her capabilities as a leader and her vulnerable side when faced with her own demons.

Nun working for the rip-off church in roanapur, also works for the CIA

Shenhua from "Black Lagoon" is a deadly and enigmatic Chinese assassin with exceptional marksmanship skills and a penchant for knives.

Le Majeur (ルマジュール Rumajūru) is a former member of Les Cinq Doigts, a five-member unit of France's Service d'Action Civique (SAC). One mission she had as a member was to go to Roanapur and hunt down a man called "La Mouche." Her name is French for "middle finger," also being her code name in Les Cinq Doigts.